I had a problem and found the solution, so I’m posting incase anyone Googles and come across this. 
Ever since I formatted my computer, I’d hear a constant high-pitched sound coming out of my headphones (very faint) and it’d change in pitch every time I moved my mouse. Turns out muting my line-in in my sound control panel fixed it. Some type of interference I guess.
Hope this helps anyone having the same problem.
It might be handy if you post what kind of motherboard you have?
http://www.viper007bond.com/about/my-computer/c2d-e6750/
It sounds like the classic CPU RF interference problem. I have it with my laptop, and there’s a number of factors involved (poor quality switching power supply, my CPU leaking Radio Frequency interference into surrounding circuitry and a poorly shielded audio interface).
I found if I isolated my power supply from the ground – effectively lifting the earth, a pretty dodgy thing to do safety-wise – the noise all but disappeared. However, it can happen with many, MANY onboard chipsets on desktop motherboards, and there’s little you can do sometimes. However, consider changing the power supply if you have a budget unit inside the machine.
Also, make sure your PC, audio equipment is all on a common ground – this can help. Also, try running your PC through a UPS (which will filter the incoming mains AC and generate its own, far purer, AC current).
It’s a bugger trying to get these sounds to go away though! I’ve known people to drive copper stakes into their garden (literally, earthing directly) and setting up an entirely isolated ringmain just for their audio equipment…
I’m on a UPS, it’s an old Audigy 2 ZS audio card (not onboard), and an Antec NeoPower 650W PSU from a few years back.
Oddly it didn’t do any of this pre-format, although I was using the basic Creative drivers from Windows Update at the time of this post.
Curious. Have you tried the kX Drivers? I think they’re compatible with the outboard Audigy 2… (I have a PCI Audigy 2 Value, it’s never let me down all these years and its ASIO performance is outstanding with the kX drivers! I’m using the ProFX drivers for better I/O but I used stock kX for years with no complaints).
Muting the Line In, if you’ve got nothing plugged in, sounds like the RF intereference from your CPU’s still leaking into the circuit somewhere – or you have an unbalanced circuit somewhere, a loaded capacitor or something. (has your signal flow changed outside of the ZS at all? Any impedance imbalances?)
Have you tried just plugging in any old device into the Line In, even if it’s turned off, and seeing if the noise persists?
The noise has stopped now that I muted my unused line-in, so I’m not terribly worried about tracking down why it was doing it. I’m just happy it’s gone.
But for how long? …
I had the same problem on Windows 7 with an Audigy card, disabling the microphone boost solved it for me.
!! Solution Ahead !!
Well that was a frustrating day so I wanted to go ahead and post what finally worked for me in all the places I’ve looked.
So I head this annoying problem of hum / buzz / hiss / high pitch computer noise whenever I had HD activity or scroll the screen with the mouse.
I have:
Cakewalk UA-1G USB Audio Interface (Soundcard)
M-Audio BX5a Monitors
The noise was happening only when the USB cable from the soundcard was connected through the computer.
I have tried most of the things I’ve read (luckily I had everything needed):
(Non of these helped)
- Mute every input source (Mic, line-in, etc)
- Disable onboard sound
- Connect the USB sound card to an external, self powered USB hub
- Installed a PCI USB card in connected the USB sound card to it
- Connect the ground from a USB cable directly to a wall ground (tried a cable tv and AC outlets to no use)
- Different BIOS settings (Spread Spectrum, Voltages, IRQ, etc)
- Different software settings (From windows and from the UA-1G interface)
The only thing that worked:
–> Disconnect the ground from the speakers!
For me it was easy as I had cables which had ground connectors for a different region which uses a male ground pin from the power outlet. Here were I live we use a female ground pin in the outlet so the cable I happen to have had only 2 PINs and therefore practically disconnected the ground from the speakers outlets.
Silence, finally!
The phenomena is called ‘Ground Loop’ or ‘Earth Loop’ AFAIK, since for me it got resolved and I didn’t care having the speakers not grounded I didn’t continue to research the subject.
Just for your information, next on my list of things to try were:
1. Hum eliminators
2. Balanced cables (which my monitors support but my Audio Interface didn’t)
Hope this help and saves someone time,
Best of luck
Ron
hahaha thank you I was just having this problem
a quicker way is to lower the volume on the headphones themself then up the pc volume … works for me no buzzing